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Rademikibart

CAT: 0931-T81314-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T81314-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2648260-80-2
Target
IL Receptor, Interleukin
Related Pathways
Immunology/Inflammation
Purity
0.983
Bioactivity
Rademikibart (CBP-201) is a humanised monoclonal antibody targeting IL-4Rα (KD = 20.7 pM) that does not interact with IL-4Rα from other species. Rademikibart inhibits IL-4 and IL-13-mediated STAT6 signalling pathways, TF-1 cell proliferation, and TARC production in PBMCs, making it useful for studying Th2-type inflammatory diseases.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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