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Retrocyclin-1

CAT: 0931-T81295-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0931-T81295-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
724760-19-4
Target
HIV Protease|||P-gp
Related Pathways
Membrane transporter/Ion channel|||Microbiology/Virology|||Neuroscience|||Proteases/Proteasome
Bioactivity
Retrocyclin-1, a Theta-defensin, selectively binds to carbohydrate-rich surface molecules such as fetuin, gp120 (K d =35.4 nM), CD4 (K d =31 nM), and galactosylceramide (K d =24.1 nM) [1], thereby shielding cells from HIV-1 infection.
Smiles
O=C1[C@]2(NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@]3(NC(=O)[C@]([C@H](CC)C)(NC(=O)CNC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@](CSSC3)(NC(=O)[C@]([C@H](CC)C)(NC(=O)[C@](CSSC2)(NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@]4(CSSC[C@](NC(=O)[C@]([C@H](CC)C)(N1)[H])(C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)N[C@@]([C@H](CC)C)(C(=O)N4)[H])[H])[H])[H])[H])[H])[H])[H])[H]
Molecular Formula
C74H128N30O18S6
Molecular Weight
1918.39
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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