RIOK2-IN-1

CAT: 0931-T81272-01Size: 5 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0931-T81272-01Size:5 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

CAS Number

1088216-72-1

Target

Serine/threonin kinase, Others

Related Pathways

Cell Cycle/Checkpoint, Metabolism, Others

Bioactivity

RIOK2-IN-1 (com 4) is a selective RIOK2 inhibitor with a Kd of 150 nM, though it has low cellular activity with an IC50 of 14,600 nM. RIOK2, an atypical kinase, is involved in ribosome maturation and cell cycle progression and is associated with various human cancers. The derivative compound CQ211, an enhanced version of RIOK2-IN-1, shows robust in vivo and in vitro efficacy, effectively inhibiting the proliferation of MKN-1 and HT-29 cancer cell lines and hindering tumor growth in the MKN-1 mouse xenograft model [1].

Smiles

O=C(NC1=NC=CC(=C1)C)CC=2C=CC=3C=CC=CC3C2

Molecular Formula

C18H16N2O

Molecular Weight

276.33

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Related Products

Catalog	Name
T5790-01	1,1,1,1-Kestohexaose
T83125-01	AMPK-α1β1γ1 activator 1
T40476	1,1,1-Tribromoacetone
T78868-01	TWIK-1/TREK-1-IN-1
T39182	1-Bromo-1,1-dichloroacetone
T39162	1,1,1,3-Tetrachloroacetone
T73743-01	1,1′,1′′,1′′′-[1,4-Piperazinediylbis (2,1-ethanediylnitrilo) ]tetrakis[2-dodecanol]
T211817-01	C22:1 1-Deoxyceramide (m18:1/22:1)
TMAC-02586-01	Anti-RIOX2 Antibody (4P713)
T209355-01	Bfl-1-IN-1

Alternative Products

Catalog	Name
MBS5822925	RIOK2-IN-1
574847-01	RIOK2
P28994	PExpress-1-Riok2 (rat)
PVT38108	pExpress-1-Riok2 Plasmid
70R-3723	RIOK2 antibody
541856-01	RIOK2 discontinued
MBS517523-01	RIOK2 Protein
574849-01	RIOK2 (FITC)
MBS5822924	RIOK2-IN-2
574848-01	RIOK2 (Biotin)

RIOK2-IN-1

Related Products

Alternative Products

Popular Products