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Tetraproline

CAT: 0931-T81004-02Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0931-T81004-02Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
21866-90-0
Bioactivity
Tetraproline, a sequence fragment of tristetraprolin (TTP), facilitates the repression and degradation of mRNAs containing AU-rich elements by recruiting the 4EHP-GYF2 cap-binding complex to TTP's tetraproline motifs [1].
Smiles
C(=O)(N1[C@H](C(=O)N2[C@H](C(O)=O)CCC2)CCC1)[C@H]3N(C(=O)[C@@H]4CCCN4)CCC3
Molecular Formula
C20H30N4O5
Molecular Weight
406.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

H-Pro-pro-pro-pro-OH
CAS Number21866-90-0
PubChem CID11902983
IUPAC Name(2S)-1-[(2S)-1-[(2S)-1-[(2S)-pyrrolidine-2-carbonyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carboxylic acid
Molecular FormulaC20H30N4O5
Molecular Weight406.5
XLogP-2.2
Topological Polar Surface Area110
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count4
Heavy Atom Count29
Formal Charge0
Complexity698
SMILES
C1C[C@H](NC1)C(=O)N2CCC[C@H]2C(=O)N3CCC[C@H]3C(=O)N4CCC[C@H]4C(=O)O
InChI
InChI=1S/C20H30N4O5/c25-17(13-5-1-9-21-13)22-10-2-6-14(22)18(26)23-11-3-7-15(23)19(27)24-12-4-8-16(24)20(28)29/h13-16,21H,1-12H2,(H,28,29)/t13-,14-,15-,16-/m0/s1
InChIKey
CBNLHHITRUAXOE-VGWMRTNUSA-N
Chemical Structure
2D Structure
2D structure of H-Pro-pro-pro-pro-OH
CAS: 21866-90-0
CID: 11902983
Formula: C20H30N4O5
MW: 406.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight406.5
XLogP3-2.2
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count4
Exact Mass406.22162007
Monoisotopic Mass406.22162007
Topological Polar Surface Area110 Ų
Heavy Atom Count29
Formal Charge0
Complexity698
Isotope Atom Count0
Defined Atom Stereocenter Count4
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
HY-P4272Tetraproline

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