TMDJ-035

• Target:

  Calcium Channel

• Related Pathways:

  Membrane transporter/Ion channel|||Metabolism

• Bioactivity:

  TMDJ-035 is a selective inhibitor of the RyR2 (ryanodine receptor 2) . It effectively suppresses abnormal calcium (Ca^2+) waves and transients in isolated cardiomyocytes derived from mice with RyR2 mutations. As such, TMDJ-035 serves as a valuable tool in research for elucidating the gating mechanisms and dynamics of the RyR2 channel [1].

• Smiles:

  O=C(N(C1=CC=C(F)C=C1)C)CN2N=NC(=N2)C3=CC(F)=CC(F)=C3

• Molecular Formula:

  C16H12F3N5O

• Molecular Weight:

  347.29

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2681302-83-8