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TMDJ-035

CAT: 0931-T80975-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T80975-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2681302-83-8
Target
Calcium Channel
Related Pathways
Membrane transporter/Ion channel, Metabolism
Bioactivity
TMDJ-035 is a selective inhibitor of the RyR2 (ryanodine receptor 2) . It effectively suppresses abnormal calcium (Ca^2+) waves and transients in isolated cardiomyocytes derived from mice with RyR2 mutations. As such, TMDJ-035 serves as a valuable tool in research for elucidating the gating mechanisms and dynamics of the RyR2 channel [1].
Smiles
O=C(N(C1=CC=C(F)C=C1)C)CN2N=NC(=N2)C3=CC(F)=CC(F)=C3
Molecular Formula
C16H12F3N5O
Molecular Weight
347.29
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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