TMDJ-035

• CAS Number :

  2681302-83-8

• Target :

  Calcium Channel

• Related Pathways :

  Membrane transporter/Ion channel|||Metabolism

• Bioactivity :

  TMDJ-035 is a selective inhibitor of the RyR2 (ryanodine receptor 2) . It effectively suppresses abnormal calcium (Ca^2+) waves and transients in isolated cardiomyocytes derived from mice with RyR2 mutations. As such, TMDJ-035 serves as a valuable tool in research for elucidating the gating mechanisms and dynamics of the RyR2 channel [1].

• Smiles :

  O=C(N(C1=CC=C(F)C=C1)C)CN2N=NC(=N2)C3=CC(F)=CC(F)=C3

• Molecular Formula :

  C16H12F3N5O

• Molecular Weight :

  347.29

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C