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Tri-GalNAc-NHS ester

CAT: 0931-T80946-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T80946-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1953146-83-2
Target
LYTACs
Related Pathways
PROTAC
Bioactivity
Tri-GalNAc-NHS ester, a LYsosome TArgeting Chimera (LYTAC) and ligand for the asialoglycoprotein receptor (ASGPR), facilitates the degradation of extracellular proteins, including membrane proteins, via the lysosomal targeting receptor expressed on liver cells. This compound is utilized as a protein degrader in LYTAC research [1].
Smiles
C(NC(CCOCCOCCOCCOCCOCCC(ON1C(=O)CCC1=O)=O)=O)(COCCC(NCCCNC(CCCCO[C@H]2[C@H](NC(C)=O)[C@@H](O)[C@@H](O)[C@@H](CO)O2)=O)=O)(COCCC(NCCCNC(CCCCO[C@H]3[C@H](NC(C)=O)[C@@H](O)[C@@H](O)[C@@H](CO)O3)=O)=O)COCCC(NCCCNC(CCCCO[C@H]4[C@H](NC(C)=O)[C@@H](O)[C@@H](O)[C@@H](CO)O4)=O)=O
Molecular Formula
C79H137N11O37
Molecular Weight
1832.98
Shipping Conditions
Ice Packs
Storage Temperature
-20°C