WAY-649123

• Target:

  Others

• Related Pathways:

  Others

• Bioactivity:

  WAY-649123 is an active molecule that exhibits (in vitro) antagonistic properties against (alpha-1A adrenergic receptors), with a (pKi) of 8.9. It also demonstrates a 70-fold selectivity over (alpha-1B) and 100-fold selectivity over (alpha-1D) subtypes. This compound has been shown to cross the blood-brain barrier (BBB) effectively in preclinical trials. Furthermore, WAY-649123 exhibits a high level of oral bioavailability and a favorable pharmacokinetic profile, making it a potential candidate for clinical development targeting conditions associated with (alpha-1A) receptors.

• Smiles:

  O=C(NC1=CC=C(F)C=C1F)CC2=CC=C3OCCOC3=C2

• Molecular Formula:

  C16H13F2NO3

• Molecular Weight:

  305.28

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  801244-46-2