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π-TRTX-Hm3a

CAT: 0931-T80429-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T80429-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Sodium Channel
Related Pathways
Membrane transporter/Ion channel
Bioactivity
π-TRTX-Hm3a, a 37-amino acid peptide derived from the venom of the Togo starburst tarantula (Heteroscodra maculata), selectively inhibits the acid-sensing ion channel 1a (ASIC1a) in a pH-dependent manner, with an inhibitory concentration half-max (IC50) of 1-2 nM, and also potentiates the activity of acid-sensing ion channel 1b (ASIC1b) with an effective concentration half-max (EC50) of 46.5 nM [1].
Molecular Formula
C186H290N56O49S6
Molecular Weight
4287.03
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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HY-P5780π-TRTX-Hm3a
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