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Conopeptide rho-TIA

CAT: 0931-T80175-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T80175-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
381725-58-2
Target
Adrenergic Receptor
Related Pathways
Neuroscience, GPCR/G Protein
Bioactivity
Conopeptide rho-TIA, a peptide from Conus tulipa venom, acts as a selective, noncompetitive inhibitor at the human α1B-Adrenergic Receptor and as a competitive inhibitor at the α1A and α1D-Adrenergic Receptors. Binding to these subtypes, conopeptide rho-TIA may inform the creation of new α1-Adrenergic Receptor subtype-selective drugs [1].
Smiles
C([C@@H](C(N[C@H](C(N[C@@H]1C(=O)N[C@@]2(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@]([C@H](CC)C)(C(=O)N3[C@](C(=O)N[C@@H](C)C(=O)N[C@@](CSSC1)(C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC4=CN=CN4)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC5=CC=CC=C5)C(=O)N[C@H](C(N)=O)CSSC2)[H])(CCC3)[H])[H])[H])=O)CCCNC(=N)N)=O)NC([C@@H](NC([C@H](CC6=CC=CC=C6)N)=O)CC(N)=O)=O)C=7C=8C(NC7)=CC=CC8
Molecular Formula
C105H160N36O21S4
Molecular Weight
2390.88
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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