Guvacine hydrobromide

• Target:

  GABA Receptor

• Related Pathways:

  Neuroscience|||Membrane transporter/Ion channel

• Bioactivity:

  Guvacine hydrobromide, an alkaloid derived from the Areca catechu nut, serves as a potent inhibitor of GABA (GABA uptakp) uptake. It effectively inhibits rat GABA transporter isoforms GAT-1, GAT-2, and GAT-3, with respective IC50 values of 39 ?M, 58 ?M, and 378 ?M [1].

• Smiles:

  Br.O=C (O) C1=CCCNC1

• Molecular Formula:

  C6H10BrNO2

• Molecular Weight:

  208.05

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  6027-92-5