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Antimycin A2c

CAT: 0931-T79941-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T79941-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Apoptosis
Related Pathways
Apoptosis
Bioactivity
Anticancer Agent 141 (Compound AE), an antimycin alkaloid, exhibits inhibitory potential against HPV-infected cervical cancer. It impedes HeLa cell proliferation by arresting the cell cycle at the S phase and induces caspase-dependent apoptosis through mitochondrial disruption. This disruption activates the ROS-mediated ubiquitin-dependent proteasome system, leading to the degradation of E6/E7 oncoproteins [1].
Molecular Formula
C28H40N2O9
Molecular Weight
548.63
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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