GRK2 Inhibitor 2

CAT: 0931-MF-0157540-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0157540-01Size:5 mg
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CAS Number
2592436-21-8
Target
Aurora Kinase|||Others|||GRK
Related Pathways
Cell Cycle/Checkpoint|||GPCR/G Protein|||Others|||Chromatin/Epigenetic
Bioactivity
GRK2 Inhibitor 2 (Compound 8h), with an IC50 of 19 nM for GRK2 and 137 nM for Aurora-A, enhances ?-AR-mediated cAMP accumulation in GRK2-overexpressing HEK293 cells. It is utilized in congestive heart failure (HF) research [1].
Smiles
O=C1C=2C(=CC=C(C2)C=3C=NNC3)C=NN1CC4=CC(OC)=CC=C4
Molecular Formula
C19H16N4O2
Molecular Weight
332.36
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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