Products for Research Use Only

PIK5-12d

CAT: 0931-T79668Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T79668Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
PROTACs, PROTAC Linker, Autophagy, PI3K
Related Pathways
PROTAC, Autophagy, PI3K/Akt/mTOR signaling
Purity
0.999
Bioactivity
PIK5-12d is a PROTAC PIKfyve degrader with antitumor activity that induces massive cytoplasmic vacuolization and blocks autophagic flow. PIK5-12d inhibits the value-added of cancer cells and can be used in the study of prostate cancer.
Smiles
CC1=CC=CC(/C=N/NC2=NC(OCCC3=CC=C(NC(CCCCC(N[C@H](C(N4C[C@H](O)C[C@H]4C(NCC5=CC=C(C6=C(C)N=CS6)C=C5)=O)=O)C(C)(C)C)=O)=O)C=C3)=NC(N7CCOCC7)=C2)=C1
Molecular Formula
C52H64N10O7S
Molecular Weight
973.19
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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