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WLB-89462

CAT: 0931-T79666-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T79666-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2849471-75-4
Target
Sigma receptor
Related Pathways
GPCR/G Protein
Bioactivity
WLB-89462 (Compound 20c) is a selective σ2 receptor ligand with a K i of 13 nM, demonstrating neuroprotective properties and the capacity to ameliorate Aβ peptide-induced short-term memory impairment in rats. It exhibits a favorable ADMET profile, featuring good solubility, lack of CYP inhibition, strong metabolic stability, high permeability, effective brain penetration, and significant oral exposure in rodent models [1].
Smiles
C(C)C=1N=C(C(=CN1)C2=CC(C)=NO2)C3CCN(CC(=O)N4CCOCC4)CC3
Molecular Formula
C21H29N5O3
Molecular Weight
399.49
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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CatalogName
T88466-01WLB-87848

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CatalogName
MBS5821327WLB-89462
HY-158693WLB-87848

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