RUNX-IN-2

• Target:

  Apoptosis

• Related Pathways:

  Apoptosis

• Bioactivity:

  RUNX-IN-2 (Compound Conjugate 3) covalently attaches to RUNX-binding sequences, preventing RUNX proteins from associating with their targets, thereby inhibiting cancer cell proliferation and inducing p53-dependent apoptosis. Furthermore, RUNX-IN-2 suppresses tumor development in PANC-1 xenograft mice and demonstrates notable alkylation efficiency and specificity [1].

• Smiles:

  N (C (=O) C1=NC (NC (=O) C2=NC (NC (CCNC (CCCC3=CC=C (N (CCCl) CCCl) C=C3) =O) =O) =CN2C) =CN1C) C=4C=C (C (NC=5N=C (C (NCCCC (NC=6C=C (C (NC=7C=C (C (NC=8C=C (C (NC=9C=C (C (NCCCN (C) C) =O) N (C) C9) =O) N (C) C8) =O) N (C) C7) =O) N (C) C6) =O) =O) N (C) C5) =O) N (C) C4

• Molecular Formula:

  C71H88Cl2N24O11

• Molecular Weight:

  1524.52

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2893777-88-1