RUNX-IN-2

• Target :

  Apoptosis

• Related Pathways :

  Apoptosis

• Bioactivity :

  RUNX-IN-2 (Compound Conjugate 3) covalently attaches to RUNX-binding sequences, preventing RUNX proteins from associating with their targets, thereby inhibiting cancer cell proliferation and inducing p53-dependent apoptosis. Furthermore, RUNX-IN-2 suppresses tumor development in PANC-1 xenograft mice and demonstrates notable alkylation efficiency and specificity [1].

• Smiles :

  N(C(=O)C1=NC(NC(=O)C2=NC(NC(CCNC(CCCC3=CC=C(N(CCCl)CCCl)C=C3)=O)=O)=CN2C)=CN1C)C=4C=C(C(NC=5N=C(C(NCCCC(NC=6C=C(C(NC=7C=C(C(NC=8C=C(C(NC=9C=C(C(NCCCN(C)C)=O)N(C)C9)=O)N(C)C8)=O)N(C)C7)=O)N(C)C6)=O)=O)N(C)C5)=O)N(C)C4

• Molecular Formula :

  C71H88Cl2N24O11

• Molecular Weight :

  1524.52

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2893777-88-1