3,7-DMF

• Target:

  TGF-beta/Smad

• Related Pathways:

  Stem Cells

• Bioactivity:

  3,7-Dimethylfumarate (3,7-DMF) serves as an oral inhibitor of transforming growth factor-beta 1 (TGF-?1) -mediated hepatic stellate cell (HSC) activation. By inducing antioxidant gene expression and scavenging reactive oxygen species (ROS), 3,7-DMF is useful for researching liver fibrosis [1].

• Smiles:

  O(C)C1=C(OC=2C(C1=O)=CC=C(OC)C2)C3=CC=CC=C3

• Molecular Formula:

  C17H14O4

• Molecular Weight:

  282.29

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  20950-52-1