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MTP

CAT: 0931-T79602-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T79602-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2377372-62-6
Target
Apoptosis, Reactive Oxygen Species, JAK, Autophagy
Related Pathways
NF-κB, Immunology/Inflammation, Angiogenesis, Autophagy, Stem Cells, JAK/STAT signaling, Apoptosis, Metabolism, Tyrosine Kinase/Adaptors, Chromatin/Epigenetic
Bioactivity
MTP, a PKM2 inhibitor, promotes apoptosis in cancer cells via caspase-3 activation while also inducing autophagy and enhancing ROS generation. Further, it inhibits JAK2 signaling, rendering it useful for the study of oral squamous cell carcinoma [1].
Smiles
C(CC(NC)=O)C=1C=C(N(N1)C2=CC=C(NC(C#C)=O)C=C2)C3=CC=C(C=C3)C4=CC=C(C(F)(F)F)C=C4
Molecular Formula
C29H23F3N4O2
Molecular Weight
516.51
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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