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DdUTP

CAT: 0931-T79579-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T79579-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
84445-38-5
Target
Reverse Transcriptase
Related Pathways
Microbiology/Virology
Bioactivity
DdUTP (2′,3′-Dideoxyuridine-5′-triphosphate) is a selective inhibitor of HIV and AMV reverse transcriptases, with Ki values of 0.05 μM for HIV and 1 μM for AMV. It is preferentially incorporated at dTTP sites within the DNA strand, thereby preventing further chain elongation [1].
Smiles
[O-]P([O-])(=O)OP([O-])(=O)OP([O-])(=O)OC[C@@H]1CC[C@@H](O1)n1ccc(=O)[nH]c1=O
Molecular Formula
C9H15N2O13P3
Molecular Weight
448.111
Shipping Conditions
Ice Packs
Storage Temperature
-20°C