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Antifungal agent 68

CAT: 0931-T79550-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T79550-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2925307-53-3
Target
Antifungal, Others
Related Pathways
Microbiology/Virology, Others
Bioactivity
Antifungal agent 68 (compound 10) effectively combats fungal infections caused by Candida and Cryptococcus gattii through the inhibition of ergosterol biosynthesis, likely via interaction with lanosterol 14α-demethylase (CYP51) . The imidazole ring of antifungal agent 68 is proposed to interact with the heme group of CYP51 [1].
Smiles
O(CC(CN1C=CN=C1)OCC2=CC=C(Cl)C=C2)C3=C(OC)C=C(CCC)C=C3
Molecular Formula
C23H27ClN2O3
Molecular Weight
414.93
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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