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BLT2 antagonist-1

CAT: 0931-T79418-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T79418-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2069220-61-5
Target
Leukotriene Receptor
Related Pathways
GPCR/G Protein
Bioactivity
BLT2 antagonist-1 (compound 15b) is a selective inhibitor of the BLT2 receptor, impeding the chemotaxis of CHO-BLT2 cells at an IC50 of 224 nM without affecting CHO-BLT1 cell chemotaxis. It blocks the interaction between LTB4 and the BLT2 receptor with a K_i of 132 nM and may serve as a research tool for inflammatory airway diseases, including asthma and chronic obstructive pulmonary disease [1].
Smiles
N(CC1=CC=C(C=C1)C2=CC=C(OCC(O)=O)C=C2)(C(CCCC)=O)C3=CC(F)=CC=C3
Molecular Formula
C26H26FNO4
Molecular Weight
435.49
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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