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Antifungal agent 72

CAT: 0931-T79384-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T79384-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
Antifungal, Others
Related Pathways
Others, Microbiology/Virology
Bioactivity
Antifungal agent 72 (Compound B8) demonstrates potent activity by inhibiting the efflux pump function and downregulating resistance-associated genes via disruption of the Pdr1-KIX interaction (K i : 11.7 μM) . It exhibits efficacy against Fluconazole-resistant strains, evidenced by a MIC of 63 ng/mL, and displays synergistic effects when combined with Fluconazole. This compound is particularly useful for researching C. glabrata infections [1].
Molecular Formula
C13H14N4OS
Molecular Weight
274.34
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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