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DZD1516

CAT: 0931-T79297-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T79297-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2387570-00-3
Target
EGFR
Related Pathways
Tyrosine Kinase/Adaptors, Angiogenesis, JAK/STAT signaling
Bioactivity
DZD1516, a potent and selective HER2 inhibitor (IC50 = 0.56 nM), demonstrates good blood-brain barrier permeability and exhibits antitumor activity in both central nervous system (CNS) and subcutaneous xenograft mouse models [1].
Smiles
O(C=1C=2C(NC3=CC(C)=C(OC4=CC=5N(C=C4)N=CN5)C=C3)=NC=NC2C=C(OC)C1)[C@@H]6C(F)(F)CN(C)CC6
Molecular Formula
C28H27F2N7O3
Molecular Weight
547.56
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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