MCI

• Target :

  Reactive Oxygen Species|||COX

• Related Pathways :

  Neuroscience|||Metabolism|||Immunology/Inflammation|||NF-?B

• Bioactivity :

  MCI, a chemical compound demonstrating significant anti-inflammatory effects, particularly in collagen-induced arthritis (CIA) models, modulates inflammation through macrophage reprogramming by enhancing ROS scavenging and promoting COX-2 downregulation. It effectively inhibits COX-2, exhibiting an IC50 of 1.23 ?M. Additionally, MCI holds potential for research applications in rheumatoid arthritis (RA) [1].

• Molecular Formula :

  C45H52ClN7O13

• Molecular Weight :

  934.39

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C