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MCI

CAT: 0931-T79260-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T79260-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Reactive Oxygen Species, COX
Related Pathways
Neuroscience, Metabolism, Immunology/Inflammation, NF-κB
Bioactivity
MCI, a chemical compound demonstrating significant anti-inflammatory effects, particularly in collagen-induced arthritis (CIA) models, modulates inflammation through macrophage reprogramming by enhancing ROS scavenging and promoting COX-2 downregulation. It effectively inhibits COX-2, exhibiting an IC50 of 1.23 μM. Additionally, MCI holds potential for research applications in rheumatoid arthritis (RA) [1].
Molecular Formula
C45H52ClN7O13
Molecular Weight
934.39
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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