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MTOR inhibitor-11

CAT: 0931-T79211-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T79211-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
3033409-32-1
Target
MTOR
Related Pathways
PI3K/Akt/mTOR signaling
Bioactivity
MTOR inhibitor-11 (Compound 9) is a brain-penetrant compound that inhibits mTOR with an IC50 of 21 nM for pS6 and exhibits inhibitory activity against pCHK1 and PDE4D with IC50 values of 17.2 μM and 17.0 μM, respectively. This compound is utilized in CNS disease research [1].
Smiles
C[C@H]1N(C2=C3C(=NC(=C2)N4[C@@H](C)COCC4)N=C(N3)C5=CC=CC=N5)CCOC1
Molecular Formula
C21H26N6O2
Molecular Weight
394.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C