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S-Gem

CAT: 0931-T79198-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T79198-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2169925-98-6
Target
Autophagy, Apoptosis, Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis
Related Pathways
Cell Cycle/Checkpoint, Apoptosis, DNA Damage/DNA Repair, Autophagy
Bioactivity
S-Gem, a thioredoxin reductase (TrxR) -dependent prodrug of Gemcitabine, is selectively activated by TrxR. Studies indicate that S-Gem exhibits lower cytotoxicity than Gemcitabine [1].
Smiles
FC1(F)[C@@H](O[C@H](CO)[C@H]1O)N2C(=O)N=C(NC(OC3CSSC3)=O)C=C2
Molecular Formula
C13H15F2N3O6S2
Molecular Weight
411.4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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