S-Gem

• Target :

  Autophagy|||Apoptosis|||Nucleoside Antimetabolite/Analog|||DNA/RNA Synthesis

• Related Pathways :

  Cell Cycle/Checkpoint|||Apoptosis|||DNA Damage/DNA Repair|||Autophagy

• Bioactivity :

  S-Gem, a thioredoxin reductase (TrxR) -dependent prodrug of Gemcitabine, is selectively activated by TrxR. Studies indicate that S-Gem exhibits lower cytotoxicity than Gemcitabine [1].

• Smiles :

  FC1(F)[C@@H](O[C@H](CO)[C@H]1O)N2C(=O)N=C(NC(OC3CSSC3)=O)C=C2

• Molecular Formula :

  C13H15F2N3O6S2

• Molecular Weight :

  411.4

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2169925-98-6