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(R) -SKBG-1

CAT: 0931-T79156-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T79156-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2955634-67-8
Target
Androgen Receptor, MicroRNA
Related Pathways
Endocrinology/Hormones, Chromatin/Epigenetic
Purity
0.9725
Bioactivity
(R) -SKBG-1 is an inhibitor of the RNA-binding protein NONO, with an EC50 value of 1.5 μM in 22Rv1 cells. (R) -SKBG-1 reduces mRNA and protein expression of the androgen receptor (AR) and its splice variants (AR-FL and AR-V7), inhibits the proliferation of various cancer cells, and affects the transcriptome and proteome of cancer cells.
Smiles
S(=O)(=O)(N1[C@@H](C(NCC2=CC=C(OC)C=C2)=O)CN(C(CCl)=O)CC1)C3=CC=C(OC)C=C3
Molecular Formula
C22H26ClN3O6S
Molecular Weight
495.98
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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