PF-07284892

• Target:

  Phosphatase|||PERK

• Related Pathways:

  Metabolism|||Apoptosis

• Purity:

  0.9777

• Bioactivity:

  PF-07284892 (ARRY-558) is an orally active allosteric SHP2 inhibitor (IC50 = 21 nM) that reduces pERK expression and may be employed in solid tumour research.

• Smiles:

  N[C@H]1C2(CC=3C1=CC=CC3)CCN(CC2)C=4N=CC(SC=5C(Cl)=C(N)N=CC5)=NN4

• Molecular Formula:

  C21H22ClN7S

• Molecular Weight:

  439.96

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2498597-94-5