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DG1

CAT: 0931-T78751-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T78751-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
Others, DNA/RNA Synthesis
Related Pathways
DNA Damage/DNA Repair, Cell Cycle/Checkpoint, Others
Bioactivity
DG1 (Compound 8Nc), a Thymidylate Synthase (TS) inhibitor, impedes angiogenesis and alters metabolic reprogramming in NSCLC cells, while effectively suppressing the expression of CD26, ET-1, FGF-1, and EGF. Additionally, it notably inhibits cancer tissue proliferation in the A549 xenograft mouse model [1].
Molecular Formula
C19H17N5O5S
Molecular Weight
427.43
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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