Dim16

CAT: 0931-MF-0146983-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0146983-01Size:25 mg
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CAS Number
2743448-32-8
Target
Serine Protease|||Others
Related Pathways
Proteases/Proteasome|||Others
Bioactivity
Dim16, a dual inhibitor of PCSK9/HMG-CoAR, demonstrates potent activity with an IC50 of 19 nM against PCSK9 and significantly impedes PCSK9-LDLR interaction with an IC50 of 0.8 nM, leading to an enhanced LDL uptake in HepG2 cells [1].
Smiles
IC1=NC=C(C2=NC=C(C=3C=CC=4C=CC=CC4C3)N2CCCC(C)(C)C)N1CCCCCNC
Molecular Formula
C29H38IN5
Molecular Weight
583.55
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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