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Batoclimab

CAT: 0931-T78245-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T78245-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2187430-05-1
Target
Others
Related Pathways
Others
Purity
0.963
Bioactivity
Batoclimab (RVT-1401) is a fully humanized immunoglobulin G1 (IgG1) monoclonal antibody that specifically targets the neonatal Fc receptor (FcRn) with high affinity for the IgG-binding site on FcRn, and by competitively binding to this site, Batoclimab effectively blocks FcRn-mediated recycling of immunoglobulin G (IgG), resulting in the enhanced degradation of IgG and subsequent reductions in circulating IgG levels, making it a candidate compound for research in autoimmune diseases such as myasthenia gravis and thyroid eye disease.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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