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Nedometinib

CAT: 0931-T78209-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T78209-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2252314-46-6
Target
MEK, p38 MAPK, PERK
Related Pathways
Apoptosis, MAPK
Purity
0.9918
Bioactivity
Nedometinib (NFX-179) is a selective mitogen-activated protein kinase kinase (MEK1) inhibitor with anticancer and antitumor activity, inhibits MAPK pathway signaling in the skin, inhibits the growth of human squamous cell lines in a dose-dependent manner, and can be used to study malignant tumors.
Smiles
O=C(NOCCO)C=1C=2C=CC=NC2N(C1NC3=CC=C(I)C=C3F)C
Molecular Formula
C17H16FIN4O3
Molecular Weight
470.24
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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