Products for Research Use Only

MitoCur-1

CAT: 0931-T78158-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T78158-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Others
Related Pathways
Others
Bioactivity
MitoCur-1, a curcumin analogue, inhibits the mitochondrial antioxidative enzyme thioredoxin reductase 2 (TrxR2) and possesses electrophilic characteristics with mitochondrial-targeting capabilities. This compound specifically induces reactive oxygen species (ROS) generation, demonstrating antitumor efficacy [1].
Smiles
COC1=C(OCCC[P+](C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4)C=CC(/C=C/C(C(C)(C)C(/C=C/C5=CC=C(OCCC[P+](C6=CC=CC=C6)(C7=CC=CC=C7)C8=CC=CC=C8)C(OC)=C5)=O)=O)=C1.[Cl-].[Cl-]
Molecular Formula
C65H64Cl2O6P2
Molecular Weight
1074.05
Shipping Conditions
Ice Packs
Storage Temperature
-20°C