SIC5-6

• Target:

  Others

• Related Pathways:

  Others

• Bioactivity:

  SIC5-6 is a potent inhibitor of Separase, a substantial cysteine protease implicated in critical cellular processes such as chromosome segregation during mitosis and meiosis, DNA damage repair, centrosome disengagement and duplication, as well as spindle stabilization and elongation. Given its overexpression in many solid cancers, Separase presents an attractive target for chemotherapy [1].

• Smiles:

  O=S(=O)(C1=CC=C(I)C=C1)N2CCC(C3=CNC=4C=CC=CC43)(C5=CNC=6C=CC=CC65)CC2

• Molecular Formula:

  C27H24IN3O2S

• Molecular Weight:

  581.47

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2410846-16-9