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HMGB1-IN-1

CAT: 0931-T78056-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T78056-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Others, NOD-like Receptor (NLR), Interleukin, TNF
Related Pathways
Others, Apoptosis, Immunology/Inflammation
Bioactivity
HMGB1-IN-1 (compound 6) exhibits potent inhibition of NO production in RAW264.7 cells, with an IC50 of 15.9 ± 0.6 μM, and effectively disrupts the HMGB1/NF-κB/NLRP3 signaling pathway, demonstrating promising anti-inflammatory and anti-sepsis properties, particularly in the context of renal injury [1].
Molecular Formula
C57H75N3O15
Molecular Weight
1042.22
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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