MYC-RIBOTAC

• Target:

  PROTACs|||Apoptosis|||c-Myc

• Related Pathways:

  Apoptosis|||PROTAC|||Cell Cycle/Checkpoint

• Bioactivity:

  MYC-RIBOTAC, a ribonuclease-targeting chimera (RIBOTAC) specific to the MYC internal ribosome entry site (IRES), comprises an MYC mRNA-binding element tethered to a small molecule that recruits and activates RNase L1. This interaction promotes the degradation of MYC mRNA, subsequently reducing MYC protein levels and inducing apoptosis, thereby presenting potential applications in anticancer research [1].

• Molecular Formula:

  C55H58N10O11S

• Molecular Weight:

  1067.17

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C