Thalidomide-O-C8-COOH

• Target:

  Others|||E3 Ligase Ligand-Linker Conjugate|||Autophagy|||Apoptosis

• Related Pathways:

  PROTAC|||Others|||Apoptosis|||Autophagy

• Bioactivity:

  Thalidomide-O-C8-COOH, also known as Cereblon ligand 3, is a Thalidomide-derived compound that serves as a Cereblon (CRBN) ligand for the targeted recruitment of CRBN protein. It can be coupled via a linker to another ligand to create proteolysis-targeting chimeras (PROTACs) [1].

• Smiles:

  O=C (O) CCCCCCCCOC1=CC=CC=2C (=O) N (C (=O) C12) C3C (=O) NC (=O) CC3

• Molecular Formula:

  C22H26N2O7

• Molecular Weight:

  430.45

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2225148-51-4