Thalidomide-O-C8-COOH

CAT: 0931-MF-0156418Size: 2 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0156418Size:2 mg
Selected
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
CAS Number
2225148-51-4
Target
Others|||E3 Ligase Ligand-Linker Conjugate|||Autophagy|||Apoptosis
Related Pathways
PROTAC|||Others|||Apoptosis|||Autophagy
Bioactivity
Thalidomide-O-C8-COOH, also known as Cereblon ligand 3, is a Thalidomide-derived compound that serves as a Cereblon (CRBN) ligand for the targeted recruitment of CRBN protein. It can be coupled via a linker to another ligand to create proteolysis-targeting chimeras (PROTACs) [1].
Smiles
O=C(O)CCCCCCCCOC1=CC=CC=2C(=O)N(C(=O)C12)C3C(=O)NC(=O)CC3
Molecular Formula
C22H26N2O7
Molecular Weight
430.45
Shipping Conditions
Cool pack
Storage Temperature
-20°C

Popular Products