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S-Me-DM4

CAT: 0931-T77872-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T77872-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
890654-03-2
Target
ADC Cytotoxin
Related Pathways
Antibody-drug Conjugate/ADC Related
Bioactivity
S-Me-DM4 is an intracellular enzyme S-methylated metabolite of DM4, a maytansinoid with microtubule-depolymerizing properties and potent cytotoxicity, employed as an Antibody-Drug Conjugate (ADC) cytotoxin [1].
Smiles
C[C@]12[C@@](O1)([C@H](C)[C@@]3(C[C@](O)([C@H](OC)/C=C/C=C(\C)/CC4=CC(N(C)C(=O)C[C@@H]2OC([C@@H](N(C(CCC(SC)(C)C)=O)C)C)=O)=C(Cl)C(OC)=C4)NC(=O)O3)[H])[H]
Molecular Formula
C39H56ClN3O10S
Molecular Weight
794.39
Shipping Conditions
Ice Packs
Storage Temperature
-20°C