S-Me-DM4

• Target:

  ADC Cytotoxin

• Related Pathways:

  Antibody-drug Conjugate/ADC Related

• Bioactivity:

  S-Me-DM4 is an intracellular enzyme S-methylated metabolite of DM4, a maytansinoid with microtubule-depolymerizing properties and potent cytotoxicity, employed as an Antibody-Drug Conjugate (ADC) cytotoxin [1].

• Smiles:

  C[C@]12[C@@](O1)([C@H](C)[C@@]3(C[C@](O)([C@H](OC)/C=C/C=C(\C)/CC4=CC(N(C)C(=O)C[C@@H]2OC([C@@H](N(C(CCC(SC)(C)C)=O)C)C)=O)=C(Cl)C(OC)=C4)NC(=O)O3)[H])[H]

• Molecular Formula:

  C39H56ClN3O10S

• Molecular Weight:

  794.39

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  890654-03-2