MSU-42011

• Target:

  NOS|||Retinoid Receptor|||Ras|||Lipid|||Kras|||PERK|||NO Synthase

• Related Pathways:

  Apoptosis|||Metabolism|||Immunology/Inflammation|||MAPK

• Purity:

  0.996

• Bioactivity:

  MSU-42011 is an orally active retinoid X receptor-like (RXR) agonist. It potently inhibits the expression of iNOS, low SREBP-induced and activated RXR, and p-ERK at the protein level. MSU-42011 has demonstrated antitumor activity in a [kras]-driven mouse model of lung cancer and is effective for the treatment of preclinical [kras]-driven lung cancer with immunomodulatory activity.

• Smiles:

  N(CC(C)C)(C1=CC(C(C)(C)C)=CC(C(C)(C)C)=C1)C2=CC=C(C(O)=O)C=N2

• Molecular Formula:

  C24H34N2O2

• Molecular Weight:

  382.54

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2456434-36-7