Products for Research Use Only

Sudubrilimab

CAT: 0931-T77189Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T77189Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
PD-1/PD-L1
Related Pathways
Apoptosis, Immunology/Inflammation, Cell Cycle/Checkpoint
Bioactivity
Sudubrilimab (HS636), an Ig G1-kappa monoclonal antibody targeting PDL1, is engineered with a TGF-β1 receptor II ectodomain (TGFBR2-ECD) fused to its C-terminus. This design enables Sudubrilimab to simultaneously inhibit the PD-1/PD-L1 pathway and TGF-β bioactivity within the immunosuppressive tumor microenvironment [1].
Shipping Conditions
Ice Packs
Storage Temperature
-20°C