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Cosibelimab

CAT: 0931-T77151-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T77151-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2216751-26-5
Target
PD-1/PD-L1
Related Pathways
Immunology/Inflammation, Apoptosis, Cell Cycle/Checkpoint
Bioactivity
Cosibelimab (CK-301; TG-1501) is a fully human, high-affinity monoclonal antibody that inhibits PD-L1 by preventing its interaction with PD-1. Featuring a functional Fc domain, this compound effectively induces antibody-dependent cellular cytotoxicity (ADCC) and complement-dependent cytotoxicity (CDC), targeting and eliminating PD-L1+ cell lines, including lymphoma cells [1].
Shipping Conditions
Ice Packs
Storage Temperature
-20°C