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Tarextumab

CAT: 0931-T76829-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T76829-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1359940-55-8
Target
Gamma-secretase
Related Pathways
Neuroscience, Stem Cells, Proteases/Proteasome
Purity
0.9719
Bioactivity
Tarextumab (OMP-59R5) is a fully human IgG2 monoclonal antibody designed to selectively target and inhibit the signaling of Notch2 and Notch3 receptors. preclinical and clinical studies have demonstrated that inhibition of the Notch2/3 pathway with chemotherapeutic agents is efficacious across a broad spectrum of epithelial tumors, including breast, lung, ovarian, and pancreatic cancers, thereby establishing Tarextumab as a promising candidate for oncological research and development.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C