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Seribantumab

CAT: 0931-T76791-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T76791-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1334296-12-6
Target
EGFR, HER, Apoptosis
Related Pathways
Tyrosine Kinase/Adaptors, Angiogenesis, Apoptosis, JAK/STAT signaling
Purity
0.9626
Bioactivity
Seribantumab (MM 121) is a humanized monoclonal antibody targeting HER3, inhibiting NRG1-induced growth in MCF-7 cells and patient-derived breast and lung cancer cells harboring NRG1 fusions or amplifications. It also induces apoptosis in MDA-MB-175-VII and LUAD-0061AS3 cells.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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