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Emactuzumab

CAT: 0931-T76776-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T76776-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1448221-67-7
Target
C-Fms, TAM Receptor
Related Pathways
Tyrosine Kinase/Adaptors
Purity
0.981
Bioactivity
Emactuzumab (RG 7155) is a monoclonal antibody against colony-stimulating factor-1 receptor targeting tumor-associated macrophages (TAMs) Emactuzumab has antitumor activity and inhibits activation of colony-stimulating factor 1 receptor (CSF1R) Emactuzumab has a high affinity for CSF-1R with a Ki value of 0.2 nM. Emactuzumab blocks CSF-1R dimerization and can be used to study cancers such as diffuse tenosynovial giant cell tumor (dt-GCT) .
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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