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Emapalumab

CAT: 0931-T76742-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T76742-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1709815-23-5
Target
COX, IFNAR
Related Pathways
Neuroscience, Immunology/Inflammation
Purity
0.9756
Bioactivity
Emapalumab (NI-0501) is an IgG1 monoclonal antibody that humanizes human monoclonal antibodies against interferon gamma, blocking its binding to cell surface receptors and activating inflammatory signaling. Emapalumab has a high binding force (Kd=1.4 pM) to free IFN-γ and to IFN-γ bound to its receptor. Emapalumab can be used in the study of hemophagocytic lymphohistiocytosis (HLH) .
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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