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Lanadelumab

CAT: 0931-T76710-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T76710-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1426055-14-2
Target
Serine Protease
Related Pathways
Proteases/Proteasome
Purity
0.992
Bioactivity
Lanadelumab (SHP643) is a humanized IgG1 monoclonal antibody targeting plasma kallikrein (pKal) with a Ki value of 0.12 nM. Lanadelumab effectively inhibits both free pKal and its interaction with high molecular weight kininogen (HMWK) -bound pKal. Lanadelumab has demonstrated potential in hereditary angioedema research and represents a promising therapeutic antibody for studying kallikrein-kinin system regulation.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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