GR 83074

• Target :

  Neurokinin receptor

• Related Pathways :

  Neuroscience|||GPCR/G Protein

• Bioactivity :

  GR 83074 is a potent and selective antagonist of the NK-2 (Neurokinin Receptor) with a 340-fold selectivity over NK-1 and a pK_B value of 8.23. It does not act as an antagonist for NK-3, affirming its specificity [1].

• Smiles :

  CCCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H]1CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)OC(C)(C)C)C(N)=O

• Molecular Formula :

  C50H72N12O9

• Molecular Weight :

  985.18

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  141636-44-4