Nocistatin

• Target:

  Opioid Receptor

• Related Pathways:

  GPCR/G Protein|||Endocrinology/Hormones|||Neuroscience

• Bioactivity:

  Nocistatin, an endogenous neuropeptide, serves as a ligand for the orphan opioid receptor-like receptor and functionally antagonizes the neuropeptide nociceptin/orphanin FQ (Noc/OFQ) . It inhibits 5-HT release through a G i/o protein-mediated pathway and blocks nociceptin-induced allodynia and hyperalgesia [1] [2].

• Smiles:

  CC(C)C[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](N)CCC(O)=O)C(=O)N[C@@H](CCC(N)=O)C(O)=O

• Molecular Formula:

  C32H56N10O12

• Molecular Weight:

  772.85

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  207392-60-7