Nocistatin

• Target:

  Opioid Receptor

• Related Pathways:

  GPCR/G Protein|||Endocrinology/Hormones|||Neuroscience

• Bioactivity:

  Nocistatin, an endogenous neuropeptide, serves as a ligand for the orphan opioid receptor-like receptor and functionally antagonizes the neuropeptide nociceptin/orphanin FQ (Noc/OFQ) . It inhibits 5-HT release through a G i/o protein-mediated pathway and blocks nociceptin-induced allodynia and hyperalgesia [1] [2].

• Smiles:

  CC (C) C[C@H] (NC (=O) [C@H] (CCC (N) =O) NC (=O) [C@H] (CCCCN) NC (=O) [C@H] (CCC (N) =O) NC (=O) [C@@H] (N) CCC (O) =O) C (=O) N[C@@H] (CCC (N) =O) C (O) =O

• Molecular Formula:

  C32H56N10O12

• Molecular Weight:

  772.85

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  207392-60-7