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Cenderitide

CAT: 0931-T76334-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T76334-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
507289-11-4
Target
Guanylate cyclase
Related Pathways
GPCR/G Protein
Bioactivity
Cenderitide, a natriuretic peptide (NP) that combines C-type natriuretic peptide (CNP) with the C-terminus of Dendroaspis natriuretic peptide (DNP), serves as a potent agonist of the particulate guanylyl cyclase receptor (pGC) . By activating both pGC-A and pGC-B receptors, it stimulates the production of the second messenger cGMP, suppresses aldosterone, and maintains glomerular filtration rate (GFR) without affecting blood pressure. This compound is particularly significant in the context of heart failure research, as evidenced by references [1] [2] [3].
Molecular Formula
C158H263N49O50S3
Molecular Weight
3745.27
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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