[Ala2] Endothelin-3, human

• Target:

  Endothelin Receptor

• Related Pathways:

  GPCR/G Protein

• Bioactivity:

  [Ala2] Endothelin-3, human is a linear analog of endothelin-3 (ET-3) with Ala substituting for Cys residues. ET-3, a vasoactive peptide produced by human rhabdomyosarcoma cell lines and not expressed in non-muscle-origin human sarcoma cell lines, serves as a paracrine factor by promoting endothelial cell migration [1] [2].

• Smiles:

  C ([C@H] (NC ([C@@H] (NC ([C@@H] (NC ([C@@H] (NC ([C@@H] (NC ([C@H] (CC1=CN=CN1) NC (=O) [C@H]2NC (=O) [C@H] (CC3=CC=C (O) C=C3) NC (=O) [C@H] (CC4=CC=C (O) C=C4) NC (=O) [C@H] ([C@H] (C) C) NC (=O) [C@]5 (NC (=O) [C@H] (CCC (O) =O) NC (=O) [C@H] (CCCCN) NC (=O) [C@H] (CC (O) =O) NC (=O) [C@H] (CCCCN) NC (=O) [C@H] (CC6=CC=C (O) C=C6) NC (=O) [C@] ([C@@H] (C) O) (NC (=O) [C@H] (CC7=CC=CC=C7) NC (=O) [C@@] (NC (=O) [C@H] (C) NC (=O) [C@@H] (N) CSSC2) (CSSC5) [H]) [H]) [H]) =O) CC (C) C) =O) CC (O) =O) =O) [C@H] (CC) C) =O) [C@H] (CC) C) =O) C (O) =O) C=8C=9C (NC8) =CC=CC9

• Molecular Formula:

  C120H166N26O32S4

• Molecular Weight:

  2613.02

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2243207-08-9