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Pep19-2.5

CAT: 0931-T76273-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T76273-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1322711-38-5
Target
Pyroptosis
Related Pathways
Immunology/Inflammation, Apoptosis
Bioactivity
Pep19-2.5, a synthetic antitoxin peptide, inhibits the intracellular signaling cascade triggered by endotoxins by blocking the activity of lipopeptides (LP) and lipopolysaccharides (LPS) mediated through both transmembrane and cytosolic pattern recognition receptors (PRRs) . This action disrupts the signaling pathways that normally result in inflammation and cell pyroptosis [1].
Smiles
C([C@@H](C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC=2C=3C(NC2)=CC=CC3)C(NCC(O)=O)=O)=O)=O)NC([C@H](CC4=CC=CC=C4)NC([C@@H](NC(CNC([C@@H](NC([C@H](CC5=CC=CC=C5)NC([C@@H](NC([C@H](CC=6C=7C(NC6)=CC=CC7)NC([C@@H](NC([C@H](CC8=CC=CC=C8)NC([C@@H](NC([C@@H](NC([C@H](CC9=CC=C(O)C=C9)NC([C@@H](NC([C@@H](NC([C@@H](NC(CN)=O)CS)=O)CCCCN)=O)CCCCN)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)=O)CCCNC(=N)N)=O)=O)CCCCN)=O)=O)CCCCN)=O)=O)CCCCN)=O)=O)C=%10C=%11C(NC%10)=CC=CC%11
Molecular Formula
C135H187N37O22S
Molecular Weight
2712.23
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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